A systematic prediction of multiple drug-target interactions from chemical, genomic, and pharmacological data.

In silico prediction of drug-target interactions from heterogeneous biological data can advance our system-level search for drug molecules and therapeutic targets, which efforts have not yet reached full fruition. In this work, we report a systematic approach that efficiently integrates the chemical...

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Autores principales: Hua Yu, Jianxin Chen, Xue Xu, Yan Li, Huihui Zhao, Yupeng Fang, Xiuxiu Li, Wei Zhou, Wei Wang, Yonghua Wang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/ea40cb89e25b401ab9039e278c05af95
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