Ethoxyquin Inhibits the Progression of Murine Ehrlich Ascites Carcinoma through the Inhibition of Autophagy and LDH

Cancer cells exhibit an increased glycolysis rate for ATP generation (the Warburg effect) to sustain an increased proliferation rate. In tumor cells, the oxidation of pyruvate in the Krebs cycle is substituted by lactate production, catalyzed by LDH. In this study, we use ethoxyquin (EQ) as a novel...

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Auteurs principaux: Fekria Tayel, Magdy E. Mahfouz, Afrah F. Salama, Mohammed A. Mansour
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
LDH
Accès en ligne:https://doaj.org/article/ea435fabccb94c3cb8326b0c2fe4a5b5
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