Small Molecule Inhibitors of MERTK and FLT3 Induce Cell Cycle Arrest in Human CD8<sup>+</sup> T Cells

There is an increasing interest in the development of Receptor Tyrosine Kinases inhibitors (RTKIs) for cancer treatment, as dysregulation of RTK expression can govern oncogenesis. Among the newer generations of RTKIs, many target Mer Tyrosine Kinase (MERTK) and Fms related RTK 3 (FLT3). Next to bein...

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Autores principales: Richard M. Powell, Marlies J. W. Peeters, Anne Rahbech, Pia Aehnlich, Tina Seremet, Per thor Straten
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/ea4b29a1d4364e7390284cee2fd8917d
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