Conditional Deletion of Activating Rearranged During Transfection Receptor Tyrosine Kinase Leads to Impairment of Photoreceptor Ribbon Synapses and Disrupted Visual Function in Mice

Conditional Deletion of Activating Rearranged During Transfection Receptor Tyrosine Kinase Leads to Impairment of Photoreceptor Ribbon Synapses and Disrupted Visual Function in Mice

Purpose: The rearranged during transfection (RET) receptor tyrosine kinase plays a key role in transducing signals related to cell growth and differentiation. Ret mutant mice show abnormal retinal activity and abnormal levels and morphology of bipolar cells, yet die on the 21st day after birth as a...

Full description

Saved in:
Bibliographic Details
Main Authors: Wei-Hao Peng, Meng-Lin Liao, Wan-Chun Huang, Pei-Kang Liu, Sarah R. Levi, Yun-Ju Tseng, Chia-Ying Lee, Lung-Kun Yeh, Kuan-Jen Chen, Chung-Liang Chien, Nan-Kai Wang
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
GDNF family of ligands (GFL)
rearranged during transfection (RET)
mouse retina
ribbon synapses
Cre-loxP knockout mice
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Online Access:https://doaj.org/article/ea6c5e3eba6e4b49aa81208f1eb3b603
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/ea6c5e3eba6e4b49aa81208f1eb3b603

Similar Items