Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1

Though coronary arteries are crucial for heart function, the mechanisms guiding their formation are largely unknown. Here, Wang et al. identify a unique, endocardially-derived angiogenic precursor cell population for coronary artery formation in mice and show that a DLL4/NOTCH1/VEGFA/VEGFR2 signalin...

Full description

Saved in:
Bibliographic Details
Main Authors: Yidong Wang, Bingruo Wu, Pengfei Lu, Donghong Zhang, Brian Wu, Shweta Varshney, Gonzalo del Monte-Nieto, Zhenwu Zhuang, Rabab Charafeddine, Adam H. Kramer, Nicolas E. Sibinga, Nikolaos G. Frangogiannis, Richard N. Kitsis, Ralf H. Adams, Kari Alitalo, David J. Sharp, Richard P. Harvey, Pamela Stanley, Bin Zhou
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
Q
Online Access:https://doaj.org/article/ea93cbead9a042ce807dbd39e7d1c160
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/ea93cbead9a042ce807dbd39e7d1c160

Similar Items