Methionine aminopeptidase 2 is a key regulator of apoptotic like cell death in Leishmania donovani
Abstract We investigate the role of methionine aminopeptidase 2 (MAP2) in miltefosine induced programmed cell death (PCD) in promastigote form of L. donovani. We report that TNP-470, an inhibitor of MAP2, inhibits programmed cell death in miltefosine treated promastigotes. It inhibits the biochemica...
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Auteurs principaux: | Ritesh Kumar, Kartikeya Tiwari, Vikash Kumar Dubey |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/eae507987eb945d5a3481885f159af9c |
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