Generation of a DKK2 homozygous knockout human embryonic stem cell line using the CRISPR/Cas9 system

Dickkopf-2 (DKK2) is an antagonist of canonical Wnt signaling, which is involved in various biological processes of development, such as epidermal appendage formation and eye development. To identify underlying effects of DKK2 during embryonic development, we generated a DKK2 homozygous knockout hum...

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Détails bibliographiques
Auteurs principaux: Wang Zhang, Yuming Li, Li Wang, Tao Xin, Canwei Zhang
Format: article
Langue:EN
Publié: Elsevier 2021
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Accès en ligne:https://doaj.org/article/eb03646ec9154b79bedcec1a95cffb31
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