Generation of a DKK2 homozygous knockout human embryonic stem cell line using the CRISPR/Cas9 system
Dickkopf-2 (DKK2) is an antagonist of canonical Wnt signaling, which is involved in various biological processes of development, such as epidermal appendage formation and eye development. To identify underlying effects of DKK2 during embryonic development, we generated a DKK2 homozygous knockout hum...
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Autores principales: | Wang Zhang, Yuming Li, Li Wang, Tao Xin, Canwei Zhang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/eb03646ec9154b79bedcec1a95cffb31 |
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