Enrichment of Antigen-Specific Class-Switched B Cells from Individuals Naturally Immunized by Infection with Group A Streptococcus
ABSTRACT The low frequency of circulating antigen-specific memory B cells is a considerable obstacle in the discovery and development of human monoclonal antibodies for therapeutic application. Here, we evaluate two solid-phase isolation methods to enrich the number of antigen-specific B cells from...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2019
|
| Subjects: | |
| Online Access: | https://doaj.org/article/eb054233c1604f348cbb5d94c5de138a |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|