Single gold-bridged nanoprobes for identification of single point DNA mutations

The identification of single point mutations is an important step toward personalizing detection and treatment. Here the authors design a gold-bridged nanoparticle for sensing MutS affinities to point mutations, and compile an atlas of the affinity data for detecting BRCA1 mutations in cell lines.

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Autores principales: Xingyi Ma, Sojin Song, Soohyun Kim, Mi-sun Kwon, Hyunsook Lee, Wounjhang Park, Sang Jun Sim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/eb28fcf5d4c94403984e0e12ea52b0be
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