Single gold-bridged nanoprobes for identification of single point DNA mutations

The identification of single point mutations is an important step toward personalizing detection and treatment. Here the authors design a gold-bridged nanoparticle for sensing MutS affinities to point mutations, and compile an atlas of the affinity data for detecting BRCA1 mutations in cell lines.

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Autores principales:	Xingyi Ma, Sojin Song, Soohyun Kim, Mi-sun Kwon, Hyunsook Lee, Wounjhang Park, Sang Jun Sim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb28fcf5d4c94403984e0e12ea52b0be
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spelling	oai:doaj.org-article:eb28fcf5d4c94403984e0e12ea52b0be2021-12-02T15:35:58ZSingle gold-bridged nanoprobes for identification of single point DNA mutations10.1038/s41467-019-08769-y2041-1723https://doaj.org/article/eb28fcf5d4c94403984e0e12ea52b0be2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08769-yhttps://doaj.org/toc/2041-1723The identification of single point mutations is an important step toward personalizing detection and treatment. Here the authors design a gold-bridged nanoparticle for sensing MutS affinities to point mutations, and compile an atlas of the affinity data for detecting BRCA1 mutations in cell lines.Xingyi MaSojin SongSoohyun KimMi-sun KwonHyunsook LeeWounjhang ParkSang Jun SimNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xingyi Ma Sojin Song Soohyun Kim Mi-sun Kwon Hyunsook Lee Wounjhang Park Sang Jun Sim Single gold-bridged nanoprobes for identification of single point DNA mutations
description	The identification of single point mutations is an important step toward personalizing detection and treatment. Here the authors design a gold-bridged nanoparticle for sensing MutS affinities to point mutations, and compile an atlas of the affinity data for detecting BRCA1 mutations in cell lines.
format	article
author	Xingyi Ma Sojin Song Soohyun Kim Mi-sun Kwon Hyunsook Lee Wounjhang Park Sang Jun Sim
author_facet	Xingyi Ma Sojin Song Soohyun Kim Mi-sun Kwon Hyunsook Lee Wounjhang Park Sang Jun Sim
author_sort	Xingyi Ma
title	Single gold-bridged nanoprobes for identification of single point DNA mutations
title_short	Single gold-bridged nanoprobes for identification of single point DNA mutations
title_full	Single gold-bridged nanoprobes for identification of single point DNA mutations
title_fullStr	Single gold-bridged nanoprobes for identification of single point DNA mutations
title_full_unstemmed	Single gold-bridged nanoprobes for identification of single point DNA mutations
title_sort	single gold-bridged nanoprobes for identification of single point dna mutations
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/eb28fcf5d4c94403984e0e12ea52b0be
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Single gold-bridged nanoprobes for identification of single point DNA mutations

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