Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

Hypothalamic melanocortin-4-receptors (MC4R) regulate food preference in rodents, but their role in humans is unclear. Here, the authors perform food preference and liking tests in humans with MC4R mutations and find that they prefer fatty food more, but sweet food less, than people without MC4R mut...

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Bibliographic Details
Main Authors: Agatha A. van der Klaauw, Julia M. Keogh, Elana Henning, Cheryl Stephenson, Sarah Kelway, Victoria M. Trowse, Naresh Subramanian, Stephen O’Rahilly, Paul C. Fletcher, I. Sadaf Farooqi
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/eb2b4dcf15464d96b8270626612758c2
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