Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

Hypothalamic melanocortin-4-receptors (MC4R) regulate food preference in rodents, but their role in humans is unclear. Here, the authors perform food preference and liking tests in humans with MC4R mutations and find that they prefer fatty food more, but sweet food less, than people without MC4R mut...

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Autores principales:	Agatha A. van der Klaauw, Julia M. Keogh, Elana Henning, Cheryl Stephenson, Sarah Kelway, Victoria M. Trowse, Naresh Subramanian, Stephen O’Rahilly, Paul C. Fletcher, I. Sadaf Farooqi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eb2b4dcf15464d96b8270626612758c2
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spelling	oai:doaj.org-article:eb2b4dcf15464d96b8270626612758c22021-12-02T15:34:09ZDivergent effects of central melanocortin signalling on fat and sucrose preference in humans10.1038/ncomms130552041-1723https://doaj.org/article/eb2b4dcf15464d96b8270626612758c22016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13055https://doaj.org/toc/2041-1723Hypothalamic melanocortin-4-receptors (MC4R) regulate food preference in rodents, but their role in humans is unclear. Here, the authors perform food preference and liking tests in humans with MC4R mutations and find that they prefer fatty food more, but sweet food less, than people without MC4R mutations.Agatha A. van der KlaauwJulia M. KeoghElana HenningCheryl StephensonSarah KelwayVictoria M. TrowseNaresh SubramanianStephen O’RahillyPaul C. FletcherI. Sadaf FarooqiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-5 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Agatha A. van der Klaauw Julia M. Keogh Elana Henning Cheryl Stephenson Sarah Kelway Victoria M. Trowse Naresh Subramanian Stephen O’Rahilly Paul C. Fletcher I. Sadaf Farooqi Divergent effects of central melanocortin signalling on fat and sucrose preference in humans
description	Hypothalamic melanocortin-4-receptors (MC4R) regulate food preference in rodents, but their role in humans is unclear. Here, the authors perform food preference and liking tests in humans with MC4R mutations and find that they prefer fatty food more, but sweet food less, than people without MC4R mutations.
format	article
author	Agatha A. van der Klaauw Julia M. Keogh Elana Henning Cheryl Stephenson Sarah Kelway Victoria M. Trowse Naresh Subramanian Stephen O’Rahilly Paul C. Fletcher I. Sadaf Farooqi
author_facet	Agatha A. van der Klaauw Julia M. Keogh Elana Henning Cheryl Stephenson Sarah Kelway Victoria M. Trowse Naresh Subramanian Stephen O’Rahilly Paul C. Fletcher I. Sadaf Farooqi
author_sort	Agatha A. van der Klaauw
title	Divergent effects of central melanocortin signalling on fat and sucrose preference in humans
title_short	Divergent effects of central melanocortin signalling on fat and sucrose preference in humans
title_full	Divergent effects of central melanocortin signalling on fat and sucrose preference in humans
title_fullStr	Divergent effects of central melanocortin signalling on fat and sucrose preference in humans
title_full_unstemmed	Divergent effects of central melanocortin signalling on fat and sucrose preference in humans
title_sort	divergent effects of central melanocortin signalling on fat and sucrose preference in humans
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/eb2b4dcf15464d96b8270626612758c2
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Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

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