Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway
The role of type I interferon signalling in the control of myeloid derived suppressor cells (MDSC) activity remains controversial. Here the authors show that downregulation of type I interferon receptor is observed in MDSC from cancer patients and tumor-bearing mice and is required for the activatio...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/eb47431a860f4ab1b301c7219d4359c8 |
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