Activation of MSRV-type endogenous retroviruses during infectious mononucleosis and Epstein-Barr virus latency: the missing link with multiple sclerosis?

The etiology of multiple sclerosis (MS) is still unclear. The immuno-pathogenic phenomena leading to neurodegeneration are thought to be triggered by environmental (viral?) factors operating on predisposing genetic backgrounds. Among the proposed co-factors are the Epstein Barr virus (EBV), and the...

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Autores principales: Giuseppe Mameli, Giordano Madeddu, Alessandra Mei, Elena Uleri, Luciana Poddighe, Lucia G Delogu, Ivana Maida, Sergio Babudieri, Caterina Serra, Roberto Manetti, Maria S Mura, Antonina Dolei
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/eb501b17465442e38d579903e5873ff1
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