High-throughput framework for genetic analyses of adverse drug reactions using electronic health records.

Understanding the contribution of genetic variation to drug response can improve the delivery of precision medicine. However, genome-wide association studies (GWAS) for drug response are uncommon and are often hindered by small sample sizes. We present a high-throughput framework to efficiently iden...

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Auteurs principaux: Neil S Zheng, Cosby A Stone, Lan Jiang, Christian M Shaffer, V Eric Kerchberger, Cecilia P Chung, QiPing Feng, Nancy J Cox, C Michael Stein, Dan M Roden, Joshua C Denny, Elizabeth J Phillips, Wei-Qi Wei
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/eb60b47e605444cfae9ea2d0eeb2459b
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