Evolutionary evidence for alternative structure in RNA sequence co-variation.
Sequence conservation and co-variation of base pairs are hallmarks of structured RNAs. For certain RNAs (e.g. riboswitches), a single sequence must adopt at least two alternative secondary structures to effectively regulate the message. If alternative secondary structures are important to the functi...
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Auteurs principaux: | Justin Ritz, Joshua S Martin, Alain Laederach |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/eb75c4770e06436ba6fef1d2f36ce839 |
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