Evolutionary evidence for alternative structure in RNA sequence co-variation.

Sequence conservation and co-variation of base pairs are hallmarks of structured RNAs. For certain RNAs (e.g. riboswitches), a single sequence must adopt at least two alternative secondary structures to effectively regulate the message. If alternative secondary structures are important to the functi...

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Auteurs principaux: Justin Ritz, Joshua S Martin, Alain Laederach
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/eb75c4770e06436ba6fef1d2f36ce839
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