TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14
The proteasome-bound ubiquitinase USP14 plays an important role in determining proteasome activity and substrate specificity. Here the authors show that TRIM11, a member of the mammalian tripartite motif family, regulates USP14 and is an important activator of the proteasome.
Guardado en:
Autores principales: | Liang Chen, Guixin Zhu, Eleanor M. Johns, Xiaolu Yang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/eb78696545ab4e1d9c7dde25e577469b |
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