Mining 3D genome structure populations identifies major factors governing the stability of regulatory communities

3D genome structures are plastic and vary from cell to cell even in an isogenic sample. Here, the authors present an approach to identify frequent 3D chromatin clusters across a population of genome structures, either deconvoluted from ensemble-averaged Hi-C data or from a collection of single-cell...

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Autores principales: Chao Dai, Wenyuan Li, Harianto Tjong, Shengli Hao, Yonggang Zhou, Qingjiao Li, Lin Chen, Bing Zhu, Frank Alber, Xianghong Jasmine Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/eb79a112fe7a4473b42cfc1b36c627a7
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