Multi-Factor Regulation of the Master Modulator LeuO for the Cyclic-(Phe-Pro) Signaling Pathway in Vibrio vulnificus

Abstract LeuO plays the role of a master regulator in the cyclic-L-phenylalanine-L-proline (cFP)-dependent signaling pathway in Vibrio vulnificus. cFP, as shown through isothermal titration calorimetry analysis, binds specifically to the periplasmic domain of ToxR. Binding of cFP triggers a change i...

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Autores principales: Na-Young Park, In Hwang Kim, Yancheng Wen, Keun-Woo Lee, Sora Lee, Jeong-A Kim, Kwang-Hwan Jung, Kyu-Ho Lee, Kun-Soo Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ebc8fdc1b34548bcb931318de56002b1
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