Two energy barriers and a transient intermediate state determine the unfolding and folding dynamics of cold shock protein

Force-dependent transitions can provide insights into the free-energy landscape of proteins. Here, the authors observe the folding and unfolding dynamics of the model protein Csp using magnetic tweezers, from which a free-energy landscape with two energy barriers and a transient intermediate state i...

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Autores principales: Haiyan Hong, Zilong Guo, Hao Sun, Ping Yu, Huanhuan Su, Xuening Ma, Hu Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ebd0c07ae42e46769d108bf1a5dca73b
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