Two energy barriers and a transient intermediate state determine the unfolding and folding dynamics of cold shock protein
Force-dependent transitions can provide insights into the free-energy landscape of proteins. Here, the authors observe the folding and unfolding dynamics of the model protein Csp using magnetic tweezers, from which a free-energy landscape with two energy barriers and a transient intermediate state i...
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Main Authors: | Haiyan Hong, Zilong Guo, Hao Sun, Ping Yu, Huanhuan Su, Xuening Ma, Hu Chen |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/ebd0c07ae42e46769d108bf1a5dca73b |
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