STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment

Abstract Background In breast cancer, complex interactions between tumor cells and cells within the surrounding stroma, such as macrophages, are critical for tumor growth, progression, and therapeutic response. Recent studies have highlighted the complex nature and heterogeneous populations of macro...

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Autores principales: Emily A. Jesser, Nicholas J. Brady, Danielle N. Huggins, Patrice M. Witschen, Christine H. O’Connor, Kathryn L. Schwertfeger
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/ebd5cadb39fe444bbd34bca1f5663296
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