STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment
Abstract Background In breast cancer, complex interactions between tumor cells and cells within the surrounding stroma, such as macrophages, are critical for tumor growth, progression, and therapeutic response. Recent studies have highlighted the complex nature and heterogeneous populations of macro...
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Auteurs principaux: | Emily A. Jesser, Nicholas J. Brady, Danielle N. Huggins, Patrice M. Witschen, Christine H. O’Connor, Kathryn L. Schwertfeger |
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Format: | article |
Langue: | EN |
Publié: |
BMC
2021
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Accès en ligne: | https://doaj.org/article/ebd5cadb39fe444bbd34bca1f5663296 |
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