The structure of classical swine fever virus N(pro): a novel cysteine Autoprotease and zinc-binding protein involved in subversion of type I interferon induction.

Pestiviruses express their genome as a single polypeptide that is subsequently cleaved into individual proteins by host- and virus-encoded proteases. The pestivirus N-terminal protease (N(pro)) is a cysteine autoprotease that cleaves between its own C-terminus and the N-terminus of the core protein....

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Auteurs principaux: Keerthi Gottipati, Nicolas Ruggli, Markus Gerber, Jon-Duri Tratschin, Matthew Benning, Henry Bellamy, Kyung H Choi
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/ebdd45b1b6d74122aa1b899f2fb977b9
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