Design, synthesis, evaluation and thermodynamics of 1-substituted pyridylimidazo[1,5-a]pyridine derivatives as cysteine protease inhibitors.

Targeting papain family cysteine proteases is one of the novel strategies in the development of chemotherapy for a number of diseases. Novel cysteine protease inhibitors derived from 1-pyridylimidazo[1,5-a]pyridine representing pharmacologically important class of compounds are being reported here f...

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Autores principales: Mohd Sajid Khan, Mohd Hassan Baig, Saheem Ahmad, Shapi Ahmad Siddiqui, Ashwini Kumar Srivastava, Kumar Venkatraman Srinivasan, Irfan A Ansari
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/ec339d7965d944c58db256d573dc26df
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