Bak instead of Bax plays a key role in metformin-induced apoptosis s in HCT116 cells

Bak instead of Bax plays a key role in metformin-induced apoptosis s in HCT116 cells

Abstract Metformin (Met) exhibits anticancer ability in various cancer cell lines. This report aims to explore the exact molecular mechanism of Met-induced apoptosis in HCT116 cells, a human colorectal cancer cell line. Met-induced reactive oxygen species (ROS) increase and ROS-dependent cell death...

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Autores principales: Hongce Chen, Beini Sun, Han Sun, Lingjun Xu, Guihao Wu, Zhuang Tu, Xuecheng Cheng, Xuhong Fan, Zihao Mai, Qiling Tang, Xiaoping Wang, Tongsheng Chen
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
Materias:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Cytology
QH573-671
Acceso en línea:https://doaj.org/article/ec5ff3f3032d4cd888f7caf48a7b9838
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https://doaj.org/article/ec5ff3f3032d4cd888f7caf48a7b9838

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