Bak instead of Bax plays a key role in metformin-induced apoptosis s in HCT116 cells
Abstract Metformin (Met) exhibits anticancer ability in various cancer cell lines. This report aims to explore the exact molecular mechanism of Met-induced apoptosis in HCT116 cells, a human colorectal cancer cell line. Met-induced reactive oxygen species (ROS) increase and ROS-dependent cell death...
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Main Authors: | Hongce Chen, Beini Sun, Han Sun, Lingjun Xu, Guihao Wu, Zhuang Tu, Xuecheng Cheng, Xuhong Fan, Zihao Mai, Qiling Tang, Xiaoping Wang, Tongsheng Chen |
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Format: | article |
Language: | EN |
Published: |
Nature Publishing Group
2021
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Online Access: | https://doaj.org/article/ec5ff3f3032d4cd888f7caf48a7b9838 |
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