Bak instead of Bax plays a key role in metformin-induced apoptosis s in HCT116 cells

Abstract Metformin (Met) exhibits anticancer ability in various cancer cell lines. This report aims to explore the exact molecular mechanism of Met-induced apoptosis in HCT116 cells, a human colorectal cancer cell line. Met-induced reactive oxygen species (ROS) increase and ROS-dependent cell death...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hongce Chen, Beini Sun, Han Sun, Lingjun Xu, Guihao Wu, Zhuang Tu, Xuecheng Cheng, Xuhong Fan, Zihao Mai, Qiling Tang, Xiaoping Wang, Tongsheng Chen
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
Sujets:
Accès en ligne:https://doaj.org/article/ec5ff3f3032d4cd888f7caf48a7b9838
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!