Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

Yolk sac erythro-myeloid progenitors (EMPs) are critical for embryo viability and a major source of adult tissue-resident macrophages. Here, the authors show an essential stage-specific role for Ezh2 in modulating Wnt signaling during EMP generation.

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Auteurs principaux: Wen Hao Neo, Yiran Meng, Alba Rodriguez-Meira, Muhammad Z. H. Fadlullah, Christopher A. G. Booth, Emanuele Azzoni, Supat Thongjuea, Marella F. T. R. de Bruijn, Sten Eirik W. Jacobsen, Adam J. Mead, Georges Lacaud
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/ed0b6a3fcda745e28ef592ad042e36dd
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Internet

https://doaj.org/article/ed0b6a3fcda745e28ef592ad042e36dd

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