Tetracyclines Diminish In Vitro IFN-γ and IL-17-Producing Adaptive and Innate Immune Cells in Multiple Sclerosis

Tetracyclines Diminish In Vitro IFN-γ and IL-17-Producing Adaptive and Innate Immune Cells in Multiple Sclerosis

IntroductionLimited data from clinical trials in multiple sclerosis (MS) reported that minocycline, a widely used antibiotic belonging to the family of tetracyclines (TCs), exerts a beneficial short-lived clinical effect A similar anti-inflammatory effect of minocycline attributed to a deviation fro...

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Main Authors: Despoina T. Florou, Athanasios Mavropoulos, Efthymios Dardiotis, Vana Tsimourtou, Vasileios Siokas, Athina-Maria Aloizou, Christos Liaskos, Christina Tsigalou, Christina Katsiari, Lazaros I. Sakkas, Georgios Hadjigeorgiou, Dimitrios P. Bogdanos
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
multiple sclerosis
doxycycline
minocycline
proinflammatory
interferon-γ
interleukin-17
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/ed1c5b548c154cf3805e7e12acf07aed
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https://doaj.org/article/ed1c5b548c154cf3805e7e12acf07aed

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