The Influence of CYP2D6 and CYP2C19 Genetic Variation on Diabetes Mellitus Risk in People Taking Antidepressants and Antipsychotics

CYP2D6 and CYP2C19 enzymes are essential in the metabolism of antidepressants and antipsychotics. Genetic variation in these genes may increase risk of adverse drug reactions. Antidepressants and antipsychotics have previously been associated with risk of diabetes. We examined whether individual gen...

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Autores principales: Isabelle Austin-Zimmerman, Marta Wronska, Baihan Wang, Haritz Irizar, Johan H. Thygesen, Anjali Bhat, Spiros Denaxas, Ghazaleh Fatemifar, Chris Finan, Jasmine Harju-Seppänen, Olga Giannakopoulou, Karoline Kuchenbaecker, Eirini Zartaloudi, Andrew McQuillin, Elvira Bramon
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/ed317ea14eac4e45bfe9e12655c30a90
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