Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage

Lipid droplets (LDs) are cellular organelles dedicated to triacylglycerol storage that can undergo fusion and dissociation events. Here the authors show that formin-like 1-dependent acto-myosin assembly on LDs facilitates their dissociation and, as a consequence, affects hydrolysis and storage of tr...

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Autores principales: Simon G. Pfisterer, Gergana Gateva, Peter Horvath, Juho Pirhonen, Veijo T. Salo, Leena Karhinen, Markku Varjosalo, Samppa J. Ryhänen, Pekka Lappalainen, Elina Ikonen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/ed431a9166504d47adae4b3f6abb8d16
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