Gut microbiome affects the metabolism of metronidazole in mice through regulation of hepatic cytochromes P450 expression

Microbiome is now considered as a significant metabolic organ with an immense potential to influence overall human health. A number of diseases that are associated with pharmacotherapy interventions was linked with altered gut microbiota. Moreover, it has been reported earlier that gut microbiome mo...

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Main Authors: Nina Zemanová, Kateřina Lněničková, Markéta Vavrečková, Eva Anzenbacherová, Pavel Anzenbacher, Iveta Zapletalová, Petra Hermanová, Tomáš Hudcovic, Hana Kozáková, Lenka Jourová
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
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Online Access:https://doaj.org/article/ed4974ecba614f2a8fbb77eaf777a40a
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