Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD<sup>+</sup>-Glycohydrolase: Evidence for Extracellular Activity

ABSTRACT Group A Streptococcus (GAS) is a common human pathogen and the etiologic agent of a large number of diseases ranging from mild, self-limiting infections to invasive life-threatening conditions. Two prominent virulence factors of this bacterium are the genetically and functionally linked por...

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Main Authors: Dóra Hancz, Elsa Westerlund, Benedicte Bastiat-Sempe, Onkar Sharma, Christine Valfridsson, Lena Meyer, John F. Love, Maghnus O’Seaghdha, Michael R. Wessels, Jenny J. Persson
Format: article
Language:EN
Published: American Society for Microbiology 2017
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Online Access:https://doaj.org/article/ed60a73db88044dd80ac2bc414eea6eb
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