Targeted radionuclide therapy with astatine-211: Oxidative dehalogenation of astatobenzoate conjugates

Abstract 211At is a most promising radionuclide for targeted alpha therapy. However, its limited availability and poorly known basic chemistry hamper its use. Based on the analogy with iodine, labelling is performed via astatobenzoate conjugates, but in vivo deastatination occurs, particularly when...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: David Teze, Dumitru-Claudiu Sergentu, Valentina Kalichuk, Jacques Barbet, David Deniaud, Nicolas Galland, Rémi Maurice, Gilles Montavon
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/ed78f40f24454144bfa69cd69a69a850
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!