Functional Inhibition of Valosin-Containing Protein Induces Cardiac Dilation and Dysfunction in a New Dominant-Negative Transgenic Mouse Model
Valosin-containing protein (VCP) was found to play a vital protective role against cardiac stresses. Genetic mutations of VCP are associated with human dilated cardiomyopathy. However, the essential role of VCP in the heart during the physiological condition remains unknown since the VCP knockout in...
Saved in:
Main Authors: | Xiaonan Sun, Ning Zhou, Ben Ma, Wenqian Wu, Shaunrick Stoll, Lo Lai, Gangjian Qin, Hongyu Qiu |
---|---|
Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/edd7597b2f3f4e32b0397aa06d10e564 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY
by: P. N. Isakhanova, et al.
Published: (2012) -
Association of ADRB2 gene polymorphism with dilated cardiomyopathy
by: Svetlana Y. Nikulina, et al.
Published: (2021) -
Functional Organization of Sequence Motifs in Diverse Transit Peptides of Chloroplast Proteins
by: Jinseung Jeong, et al.
Published: (2021) -
Miocardiopatía dilatada reversible asociada a hipotiroidismo severo
by: Pérez Baztarrica,Gabriel, et al.
Published: (2017) -
GRINL1A Complex Transcription Unit Containing GCOM1, MYZAP, and POLR2M Genes Associates with Fully Penetrant Recessive Dilated Cardiomyopathy
by: Krista Heliö, et al.
Published: (2021)