Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells

Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells

Summary: Human induced pluripotent stem cells (hiPSCs) show variable differentiation potential due to their epigenomic heterogeneity, whose extent/attributes remain unclear, except for well-studied elements/chromosomes such as imprints and the X chromosomes. Here, we show that seven hiPSC lines with...

Full description

Saved in:
Bibliographic Details
Main Authors: Shihori Yokobayashi, Yukihiro Yabuta, Masato Nakagawa, Keisuke Okita, Bo Hu, Yusuke Murase, Tomonori Nakamura, Guillaume Bourque, Jacek Majewski, Takuya Yamamoto, Mitinori Saitou
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
human induced pluripotent stem cells
clonal heterogeneity
epigenome
histone modifications
DNA methylation
X chromosome inactivation
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/ede168a2bf544c0b9ef86da849b5f0a5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/ede168a2bf544c0b9ef86da849b5f0a5

Similar Items