Germline POT1 Deregulation Can Predispose to Myeloid Malignancies in Childhood
While the shelterin complex guards and coordinates the mechanism of telomere regulation, deregulation of this process is tightly linked to malignant transformation and cancer. Here, we present the novel finding of a germline stop-gain variant (p.Q199*) in the shelterin complex gene <i>POT1<...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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MDPI AG
2021
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Accès en ligne: | https://doaj.org/article/ee2aebca508c48acb2ba60d602a81910 |
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