The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s

The HUSH complex has been implicated in repressing LINE-1 elements. Here the authors reveal that the complex negatively regulates the type I IFN response in human cells through epigenetic regulation of LINE-1 elements

Guardado en:
Detalles Bibliográficos
Autores principales: Hale Tunbak, Rocio Enriquez-Gasca, Christopher H. C. Tie, Poppy A. Gould, Petra Mlcochova, Ravindra K. Gupta, Liane Fernandes, James Holt, Annemarthe G. van der Veen, Evangelos Giampazolias, Kathleen H. Burns, Pierre V. Maillard, Helen M. Rowe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/ee339e70658d4865897566aa7c7f8a90
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!