Routes of Zika virus dissemination in the testis and epididymis of immunodeficient mice

Routes of Zika virus dissemination in the testis and epididymis of immunodeficient mice

The mechanisms of ZIKV persistence in the male reproductive tract (MRT) are poorly understood. Here, Tsetsarkin et al. applied microRNA-targeting approach to trace routes of ZIKV dissemination in the testis and epididymis and to generate immunogenic live-attenuated ZIKV vaccine candidate, restricted...

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Main Authors: Konstantin A. Tsetsarkin, Olga A. Maximova, Guangping Liu, Heather Kenney, Natalia Teterina, Marshall E. Bloom, Jeffrey M. Grabowski, Luwanika Mlera, Bianca M. Nagata, Ian Moore, Craig Martens, Emerito Amaro-Carambot, Elaine W. Lamirande, Stephen S. Whitehead, Alexander G. Pletnev
Format: article
Language:EN
Published: Nature Portfolio 2018
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Science
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Online Access:https://doaj.org/article/ee7bfcbe055342979d1b86ee82672e3a
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https://doaj.org/article/ee7bfcbe055342979d1b86ee82672e3a

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