Nucleolar and spindle associated protein 1 enhances chemoresistance through DNA damage repair pathway in chronic lymphocytic leukemia by binding with RAD51

Abstract Nucleolar and spindle-associated protein 1 (NUSAP1) is an essential regulator of mitotic progression, spindle assembly, and chromosome attachment. Although NUSAP1 acts as an oncogene involved in the progression of several cancers, the exact role of chronic lymphocytic leukemia (CLL) remains...

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Autores principales: Yang Han, Xinting Hu, Xiaoya Yun, Jiarui Liu, Juan Yang, Zheng Tian, Xin Zhang, Ya Zhang, Xin Wang
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/ee84516247dc42ed834e4a7ce073c5ad
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