Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans
Poly-ADP-ribosylation (PARylation) is a well-known regulatory event in eukaryotes but has not yet been observed in bacteria. Here, the authors solve the structure of a bacterial PAR-glycohydrolase and provide evidence for a prokaryotic PARylation machinery involved in the response to genotoxic stres...
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Auteurs principaux: | Chao-Cheng Cho, Chia-Yu Chien, Yi-Chih Chiu, Meng-Hsuan Lin, Chun-Hua Hsu |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/ee938e1dfa4b4d808584c20cfe83a6c4 |
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