Hyperacetylated chromatin domains mark cell type-specific genes and suggest distinct modes of enhancer function

Super-enhancer are usually defined by high levels of chromatin modification and associate with cell-specific gene expression. Here, the authors define hyperacetylated chromatin domains (HCDs) by using histone hyperacetylation peak breadth information and show that HCDs associated more closely with c...

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Autores principales: Sierra Fox, Jacquelyn A. Myers, Christina Davidson, Michael Getman, Paul D. Kingsley, Nicholas Frankiewicz, Michael Bulger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ee98d3c56057456481faaea3dd0b0a5f
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