Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) promotes the inflammation and apoptosis of otitis media with effusion through targeting microRNA (miR)-495 and activation of p38 MAPK signaling pathway

Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) promotes the inflammation and apoptosis of otitis media with effusion through targeting microRNA (miR)-495 and activation of p38 MAPK signaling pathway

Long non-coding RNA (lncRNA) plays a vital role in human inflammatory diseases. Our study aimed to investigate the function of lncRNA nuclear-enriched abundant transcript 1 (NEAT1) in otitis media with effusion (OME). The mRNA levels of NEAT1 and miR-495 were measured by RT-qPCR. The protein levels...

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Autores principales: Yajuan Hu, Hongjun Dong, Jingjing Huang, Jie Huang, Dandan Tao, Chao Huang, Lei Hu, Hao Xu, Yan Sun
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2021
Materias:
otitis media with effusion
neat1
mir-495
mapk
inflammation
Biotechnology
TP248.13-248.65
Acceso en línea:https://doaj.org/article/ee9e209be85a4073b4f64e9c0ba68562
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https://doaj.org/article/ee9e209be85a4073b4f64e9c0ba68562

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