Structural design principles for specific ultra-high affinity interactions between colicins/pyocins and immunity proteins
Abstract The interactions of the antibiotic proteins colicins/pyocins with immunity proteins is a seminal model system for studying protein–protein interactions and specificity. Yet, a precise and quantitative determination of which structural elements and residues determine their binding affinity a...
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Main Authors: | Avital Shushan, Mickey Kosloff |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/eebc68ecefcd47f48e1af52640e17f11 |
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