An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells

Adherens junctions (AJs) mediate cell-cell adhesion between epithelial cells but tools to study their dynamic regulation are lacking. Here the authors develop an optochemical tool to stimulate the assembly of AJs through addition of a photocleavable tool and their dissociation upon exposure to light...

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Autores principales:	Dirk Ollech, Tim Pflästerer, Adam Shellard, Chiara Zambarda, Joachim Pius Spatz, Philippe Marcq, Roberto Mayor, Richard Wombacher, Elisabetta Ada Cavalcanti-Adam
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eedcc41d33c14987b2cfb07669f2953d
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spelling	oai:doaj.org-article:eedcc41d33c14987b2cfb07669f2953d2021-12-02T16:49:13ZAn optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells10.1038/s41467-020-14390-12041-1723https://doaj.org/article/eedcc41d33c14987b2cfb07669f2953d2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14390-1https://doaj.org/toc/2041-1723Adherens junctions (AJs) mediate cell-cell adhesion between epithelial cells but tools to study their dynamic regulation are lacking. Here the authors develop an optochemical tool to stimulate the assembly of AJs through addition of a photocleavable tool and their dissociation upon exposure to light.Dirk OllechTim PflästererAdam ShellardChiara ZambardaJoachim Pius SpatzPhilippe MarcqRoberto MayorRichard WombacherElisabetta Ada Cavalcanti-AdamNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dirk Ollech Tim Pflästerer Adam Shellard Chiara Zambarda Joachim Pius Spatz Philippe Marcq Roberto Mayor Richard Wombacher Elisabetta Ada Cavalcanti-Adam An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells
description	Adherens junctions (AJs) mediate cell-cell adhesion between epithelial cells but tools to study their dynamic regulation are lacking. Here the authors develop an optochemical tool to stimulate the assembly of AJs through addition of a photocleavable tool and their dissociation upon exposure to light.
format	article
author	Dirk Ollech Tim Pflästerer Adam Shellard Chiara Zambarda Joachim Pius Spatz Philippe Marcq Roberto Mayor Richard Wombacher Elisabetta Ada Cavalcanti-Adam
author_facet	Dirk Ollech Tim Pflästerer Adam Shellard Chiara Zambarda Joachim Pius Spatz Philippe Marcq Roberto Mayor Richard Wombacher Elisabetta Ada Cavalcanti-Adam
author_sort	Dirk Ollech
title	An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells
title_short	An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells
title_full	An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells
title_fullStr	An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells
title_full_unstemmed	An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells
title_sort	optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/eedcc41d33c14987b2cfb07669f2953d
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An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells

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