Optimized design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis

Optimized design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis

Single cell RNA-sequencing can be a powerful approach to characterizing cell composition in a population of cells but is thought to be too expensive for population-scale analyses. Here, the authors show how lower coverage of more samples can increase the power to detect cell-type-specific eQTL.

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Detalles Bibliográficos
Autores principales: Igor Mandric, Tommer Schwarz, Arunabha Majumdar, Kangcheng Hou, Leah Briscoe, Richard Perez, Meena Subramaniam, Christoph Hafemeister, Rahul Satija, Chun Jimmie Ye, Bogdan Pasaniuc, Eran Halperin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/ef1aefc1013e4e05871a0a3158313e73
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https://doaj.org/article/ef1aefc1013e4e05871a0a3158313e73

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