Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D

Mechanosensation by biological membranes can be relayed by mechanical tension to ion channels. Here the authors show that phospholipase D (PLD) is activated by mechanical disruption of lipid rafts which allows PLD to mix with its substrate in the lipid membrane, and propose a kinetic model of force...

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Autores principales: E. Nicholas Petersen, Hae-Won Chung, Arman Nayebosadri, Scott B. Hansen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/ef25fc0a4a2e402685b431a30b4dbb41
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